Gripe water is a liquid, over-the-counter herbal supplement marketed to parents of infants struggling with fussiness, colic, or gas. Anecdotally, some parents find it helpful for soothing their fussy babies, but there is no scientific evidence to support its effectiveness. Gripe water typically includes herbs like fennel, ginger, and chamomile. It is advised to choose an alcohol-free formula if you decide to try it.